PoplarV1, Main, Exploration, bibRecord, 001221

Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.

Identifieur interne : 001221 ( Main/Exploration ); précédent : 001220; suivant : 001222

Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.

Auteurs : Philippe Conus [Suisse, Australie] ; Sue Cotton [Australie] ; Benno G. Schimmelmann [Suisse, Allemagne] ; Patrick D. Mcgorry [Australie] ; Martin Lambert [Allemagne]

Source :

Social psychiatry and psychiatric epidemiology [ 1433-9285 ] ; 2017.

RBID : pubmed:28477070

Descripteurs français

KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Emploi (statistiques et données numériques), Femelle (MeSH), Humains (MeSH), Jeune adulte (MeSH), Mâle (MeSH), Résultat thérapeutique (MeSH), Troubles psychotiques (thérapie), Troubles psychotiques (épidémiologie), Vie autonome (statistiques et données numériques), Échelles d'évaluation en psychiatrie (MeSH), Études de cohortes (MeSH).
MESH :
- statistiques et données numériques : Emploi, Vie autonome.
- thérapie : Troubles psychotiques.
- épidémiologie : Troubles psychotiques.
- Adolescent, Adulte, Femelle, Humains, Jeune adulte, Mâle, Résultat thérapeutique, Échelles d'évaluation en psychiatrie, Études de cohortes.

English descriptors

KwdEn :
- Adolescent (MeSH), Adult (MeSH), Cohort Studies (MeSH), Employment (statistics & numerical data), Female (MeSH), Humans (MeSH), Independent Living (statistics & numerical data), Male (MeSH), Psychiatric Status Rating Scales (MeSH), Psychotic Disorders (epidemiology), Psychotic Disorders (therapy), Treatment Outcome (MeSH), Young Adult (MeSH).
MESH :
- epidemiology : Psychotic Disorders.
- statistics & numerical data : Employment, Independent Living.
- therapy : Psychotic Disorders.
- Adolescent, Adult, Cohort Studies, Female, Humans, Male, Psychiatric Status Rating Scales, Treatment Outcome, Young Adult.

Abstract

OBJECTIVES

Most first episode psychosis (FEP) outcome studies are based on patient samples enrolled through an informed consent procedure, which may induce important biases. Our aim was to study the 18-month outcome of FEP in an epidemiological sample of patients treated at the Early Psychosis Prevention and Intervention Centre (EPPIC).

METHODS

The files of 661 FEP patients treated for up to 18 months between 1998 and 2000 were assessed. Symptomatic remission was defined as receiving a score ≤3 on the Clinical Global Impressions (CGI) scales, and functional remission as concurrent fulfillment of occupation/employment and independent living. Predictors were analyzed using stepwise logistic regression models.

RESULTS

At endpoint, 63% of FEP patients had reached symptomatic remission and 44% functional remission. Duration of untreated psychosis, baseline symptom intensity, time in service and decrease or remission of substance use, predicted both symptomatic and functional outcome. A history of suicide attempt or non-adherence to medication was linked to lower likelihood to reach symptomatic remission while pre-morbid GAF and employment at baseline were linked to functional outcome.

CONCLUSIONS

The development of early intervention strategies should be pursued, in order both to provide treatment before symptoms reach a high intensity and to maintain social integration. Specific strategies need to promote engagement, facilitate adherence to medication and to create a framework where key issues such as substance abuse co-morbidity can be addressed.

DOI: 10.1007/s00127-017-1388-7
PubMed: 28477070

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 001329
to stream Main, to step Curation: 001329

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.</title>
<author><name sortKey="Conus, Philippe" sort="Conus, Philippe" uniqKey="Conus P" first="Philippe" last="Conus">Philippe Conus</name>
<affiliation wicri:level="4"><nlm:affiliation>Treatment and Early Intervention in Psychosis Program (TIPP), Département de Psychiatrie CHUV, Université de Lausanne, Clinique de Cery, 1008, Prilly, Switzerland. philippe.conus@chuv.ch.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Treatment and Early Intervention in Psychosis Program (TIPP), Département de Psychiatrie CHUV, Université de Lausanne, Clinique de Cery, 1008, Prilly</wicri:regionArea>
<orgName type="university">Université de Lausanne</orgName>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia. philippe.conus@chuv.ch.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<wicri:noRegion>3052</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cotton, Sue" sort="Cotton, Sue" uniqKey="Cotton S" first="Sue" last="Cotton">Sue Cotton</name>
<affiliation wicri:level="1"><nlm:affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<wicri:noRegion>3052</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schimmelmann, Benno G" sort="Schimmelmann, Benno G" uniqKey="Schimmelmann B" first="Benno G" last="Schimmelmann">Benno G. Schimmelmann</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Child- and Adolescent Psychiatry, University of Bern, Bern, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Child- and Adolescent Psychiatry, University of Bern, Bern</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
</placeName>
<orgName type="university">Université de Berne</orgName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcgorry, Patrick D" sort="Mcgorry, Patrick D" uniqKey="Mcgorry P" first="Patrick D" last="Mcgorry">Patrick D. Mcgorry</name>
<affiliation wicri:level="1"><nlm:affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<wicri:noRegion>3052</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lambert, Martin" sort="Lambert, Martin" uniqKey="Lambert M" first="Martin" last="Lambert">Martin Lambert</name>
<affiliation wicri:level="3"><nlm:affiliation>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:28477070</idno>
<idno type="pmid">28477070</idno>
<idno type="doi">10.1007/s00127-017-1388-7</idno>
<idno type="wicri:Area/Main/Corpus">001329</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001329</idno>
<idno type="wicri:Area/Main/Curation">001329</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001329</idno>
<idno type="wicri:Area/Main/Exploration">001329</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.</title>
<author><name sortKey="Conus, Philippe" sort="Conus, Philippe" uniqKey="Conus P" first="Philippe" last="Conus">Philippe Conus</name>
<affiliation wicri:level="4"><nlm:affiliation>Treatment and Early Intervention in Psychosis Program (TIPP), Département de Psychiatrie CHUV, Université de Lausanne, Clinique de Cery, 1008, Prilly, Switzerland. philippe.conus@chuv.ch.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Treatment and Early Intervention in Psychosis Program (TIPP), Département de Psychiatrie CHUV, Université de Lausanne, Clinique de Cery, 1008, Prilly</wicri:regionArea>
<orgName type="university">Université de Lausanne</orgName>
<placeName><settlement type="city">Lausanne</settlement>
<region nuts="3" type="region">Canton de Vaud</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia. philippe.conus@chuv.ch.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<wicri:noRegion>3052</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Cotton, Sue" sort="Cotton, Sue" uniqKey="Cotton S" first="Sue" last="Cotton">Sue Cotton</name>
<affiliation wicri:level="1"><nlm:affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<wicri:noRegion>3052</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schimmelmann, Benno G" sort="Schimmelmann, Benno G" uniqKey="Schimmelmann B" first="Benno G" last="Schimmelmann">Benno G. Schimmelmann</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Child- and Adolescent Psychiatry, University of Bern, Bern, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Child- and Adolescent Psychiatry, University of Bern, Bern</wicri:regionArea>
<placeName><settlement type="city">Berne</settlement>
<region type="région" nuts="3">Canton de Berne</region>
</placeName>
<orgName type="university">Université de Berne</orgName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcgorry, Patrick D" sort="Mcgorry, Patrick D" uniqKey="Mcgorry P" first="Patrick D" last="Mcgorry">Patrick D. Mcgorry</name>
<affiliation wicri:level="1"><nlm:affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<wicri:noRegion>3052</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lambert, Martin" sort="Lambert, Martin" uniqKey="Lambert M" first="Martin" last="Lambert">Martin Lambert</name>
<affiliation wicri:level="3"><nlm:affiliation>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg</wicri:regionArea>
<placeName><settlement type="city">Hambourg</settlement>
<region type="land" nuts="2">Hambourg</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Social psychiatry and psychiatric epidemiology</title>
<idno type="eISSN">1433-9285</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term>
<term>Adult (MeSH)</term>
<term>Cohort Studies (MeSH)</term>
<term>Employment (statistics & numerical data)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Independent Living (statistics & numerical data)</term>
<term>Male (MeSH)</term>
<term>Psychiatric Status Rating Scales (MeSH)</term>
<term>Psychotic Disorders (epidemiology)</term>
<term>Psychotic Disorders (therapy)</term>
<term>Treatment Outcome (MeSH)</term>
<term>Young Adult (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term>
<term>Adulte (MeSH)</term>
<term>Emploi (statistiques et données numériques)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Jeune adulte (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Résultat thérapeutique (MeSH)</term>
<term>Troubles psychotiques (thérapie)</term>
<term>Troubles psychotiques (épidémiologie)</term>
<term>Vie autonome (statistiques et données numériques)</term>
<term>Échelles d'évaluation en psychiatrie (MeSH)</term>
<term>Études de cohortes (MeSH)</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Psychotic Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Employment</term>
<term>Independent Living</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Emploi</term>
<term>Vie autonome</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Psychotic Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Troubles psychotiques</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Troubles psychotiques</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Cohort Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Psychiatric Status Rating Scales</term>
<term>Treatment Outcome</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Résultat thérapeutique</term>
<term>Échelles d'évaluation en psychiatrie</term>
<term>Études de cohortes</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b>
</p>
<p>Most first episode psychosis (FEP) outcome studies are based on patient samples enrolled through an informed consent procedure, which may induce important biases. Our aim was to study the 18-month outcome of FEP in an epidemiological sample of patients treated at the Early Psychosis Prevention and Intervention Centre (EPPIC).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>The files of 661 FEP patients treated for up to 18 months between 1998 and 2000 were assessed. Symptomatic remission was defined as receiving a score ≤3 on the Clinical Global Impressions (CGI) scales, and functional remission as concurrent fulfillment of occupation/employment and independent living. Predictors were analyzed using stepwise logistic regression models.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>At endpoint, 63% of FEP patients had reached symptomatic remission and 44% functional remission. Duration of untreated psychosis, baseline symptom intensity, time in service and decrease or remission of substance use, predicted both symptomatic and functional outcome. A history of suicide attempt or non-adherence to medication was linked to lower likelihood to reach symptomatic remission while pre-morbid GAF and employment at baseline were linked to functional outcome.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>The development of early intervention strategies should be pursued, in order both to provide treatment before symptoms reach a high intensity and to maintain social integration. Specific strategies need to promote engagement, facilitate adherence to medication and to create a framework where key issues such as substance abuse co-morbidity can be addressed.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">28477070</PMID>
<DateCompleted><Year>2018</Year>
<Month>04</Month>
<Day>05</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>12</Month>
<Day>02</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1433-9285</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>52</Volume>
<Issue>9</Issue>
<PubDate><Year>2017</Year>
<Month>09</Month>
</PubDate>
</JournalIssue>
<Title>Social psychiatry and psychiatric epidemiology</Title>
<ISOAbbreviation>Soc Psychiatry Psychiatr Epidemiol</ISOAbbreviation>
</Journal>
<ArticleTitle>Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.</ArticleTitle>
<Pagination><MedlinePgn>1089-1099</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s00127-017-1388-7</ELocationID>
<Abstract><AbstractText Label="OBJECTIVES">Most first episode psychosis (FEP) outcome studies are based on patient samples enrolled through an informed consent procedure, which may induce important biases. Our aim was to study the 18-month outcome of FEP in an epidemiological sample of patients treated at the Early Psychosis Prevention and Intervention Centre (EPPIC).</AbstractText>
<AbstractText Label="METHODS">The files of 661 FEP patients treated for up to 18 months between 1998 and 2000 were assessed. Symptomatic remission was defined as receiving a score ≤3 on the Clinical Global Impressions (CGI) scales, and functional remission as concurrent fulfillment of occupation/employment and independent living. Predictors were analyzed using stepwise logistic regression models.</AbstractText>
<AbstractText Label="RESULTS">At endpoint, 63% of FEP patients had reached symptomatic remission and 44% functional remission. Duration of untreated psychosis, baseline symptom intensity, time in service and decrease or remission of substance use, predicted both symptomatic and functional outcome. A history of suicide attempt or non-adherence to medication was linked to lower likelihood to reach symptomatic remission while pre-morbid GAF and employment at baseline were linked to functional outcome.</AbstractText>
<AbstractText Label="CONCLUSIONS">The development of early intervention strategies should be pursued, in order both to provide treatment before symptoms reach a high intensity and to maintain social integration. Specific strategies need to promote engagement, facilitate adherence to medication and to create a framework where key issues such as substance abuse co-morbidity can be addressed.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Conus</LastName>
<ForeName>Philippe</ForeName>
<Initials>P</Initials>
<Identifier Source="ORCID">0000-0002-5832-1910</Identifier>
<AffiliationInfo><Affiliation>Treatment and Early Intervention in Psychosis Program (TIPP), Département de Psychiatrie CHUV, Université de Lausanne, Clinique de Cery, 1008, Prilly, Switzerland. philippe.conus@chuv.ch.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia. philippe.conus@chuv.ch.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cotton</LastName>
<ForeName>Sue</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schimmelmann</LastName>
<ForeName>Benno G</ForeName>
<Initials>BG</Initials>
<AffiliationInfo><Affiliation>Department of Child- and Adolescent Psychiatry, University of Bern, Bern, Switzerland.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>McGorry</LastName>
<ForeName>Patrick D</ForeName>
<Initials>PD</Initials>
<AffiliationInfo><Affiliation>Orygen Youth Health Research Centre, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Centre for Youth Mental Health University of Melbourne, 35 Poplar Road, Parkville Victoria, Melbourne, 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lambert</LastName>
<ForeName>Martin</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Psychosis Early Detection and Intervention Centre (PEDIC), Department for Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>05</Month>
<Day>05</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Germany</Country>
<MedlineTA>Soc Psychiatry Psychiatr Epidemiol</MedlineTA>
<NlmUniqueID>8804358</NlmUniqueID>
<ISSNLinking>0933-7954</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004651" MajorTopicYN="N">Employment</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D057187" MajorTopicYN="N">Independent Living</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011569" MajorTopicYN="N">Psychiatric Status Rating Scales</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011618" MajorTopicYN="N">Psychotic Disorders</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">First episode psychosis</Keyword>
<Keyword MajorTopicYN="Y">Functioning</Keyword>
<Keyword MajorTopicYN="Y">Outcome</Keyword>
<Keyword MajorTopicYN="Y">Predictors</Keyword>
<Keyword MajorTopicYN="Y">Schizophrenia</Keyword>
<Keyword MajorTopicYN="Y">Symptoms</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>10</Month>
<Day>31</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2017</Year>
<Month>05</Month>
<Day>01</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>5</Month>
<Day>10</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2018</Year>
<Month>4</Month>
<Day>6</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
<Month>5</Month>
<Day>7</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">28477070</ArticleId>
<ArticleId IdType="doi">10.1007/s00127-017-1388-7</ArticleId>
<ArticleId IdType="pii">10.1007/s00127-017-1388-7</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Acta Psychiatr Scand. 2009 Aug;120(2):138-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19207130</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Bull. 1980;6(4):606-18</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7444392</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biol Psychiatry. 2000 Sep 15;48(6):467-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11018220</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Can J Psychiatry. 2008 Oct;53(10):660-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18940034</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Psychiatry Res. 1997 Dec 5;73(3):159-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9481807</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Bull. 1990;16(3):501-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2287936</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Psychol Med. 2006 May;36(5):649-58</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16515734</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Early Interv Psychiatry. 2015 Feb;9(1):1-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24576137</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Res. 2016 Aug;175(1-3):57-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27050475</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Res. 2011 Jul;129(2-3):111-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21549566</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Bull. 1980;6(4):592-605</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7444391</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Acta Psychiatr Scand. 2005 Aug;112(2):141-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15992396</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Behav Modif. 2000 Apr;24(2):264-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10804683</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Psychiatry. 2005 Oct;66(10):1239-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16259537</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Psychiatry. 2005 Mar;162(3):441-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15741458</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Acta Psychiatr Scand. 2008 Sep;118(3):220-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18699954</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Acta Psychiatr Scand. 2007 Jul;116(1):54-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17559601</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Res. 2008 Dec;106(2-3):281-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18926666</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Psychiatry. 1994 Oct;151(10):1409-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8092334</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Bull. 2009 Mar;35(2):362-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18990715</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nervenarzt. 1990 May;61(5):259-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2193235</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Acta Psychiatr Scand. 2006 Nov;114(5):337-45</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17022793</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Bull. 2015 May;41(3):617-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25381449</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Br J Psychiatry Suppl. 1998;172(33):14-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9764121</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Soc Psychiatry Psychiatr Epidemiol. 2010 Jan;45(1):1-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19305936</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Acta Psychiatr Scand. 2009 Aug;120(2):129-37</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19392808</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Br J Psychiatry. 2008 Aug;193(2):114-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18669993</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Gen Psychiatry. 2008 Jul;65(7):762-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18606949</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Nerv Ment Dis. 2009 May;197(5):362-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19440110</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Am Acad Child Adolesc Psychiatry. 2006 Aug;45(8):990-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16865042</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Gen Psychiatry. 2005 Sep;62(9):975-83</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16143729</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Psychol Med. 2014 Jan;44(1):117-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23590927</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Res. 2002 Oct 1;57(2-3):209-19</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12223252</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Psychol Med. 2006 Oct;36(10):1349-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16756689</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Bull. 1990;16(3):517-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2287937</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Psychol Med. 1996 Jan;26(1):161-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8643756</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Suisse</li>
</country>
<region><li>Canton de Berne</li>
<li>Canton de Vaud</li>
<li>Hambourg</li>
<li>Victoria (État)</li>
</region>
<settlement><li>Berne</li>
<li>Hambourg</li>
<li>Lausanne</li>
<li>Melbourne</li>
</settlement>
<orgName><li>Université de Berne</li>
<li>Université de Lausanne</li>
<li>Université de Melbourne</li>
</orgName>
</list>
<tree><country name="Suisse"><region name="Canton de Vaud"><name sortKey="Conus, Philippe" sort="Conus, Philippe" uniqKey="Conus P" first="Philippe" last="Conus">Philippe Conus</name>
</region>
<name sortKey="Schimmelmann, Benno G" sort="Schimmelmann, Benno G" uniqKey="Schimmelmann B" first="Benno G" last="Schimmelmann">Benno G. Schimmelmann</name>
</country>
<country name="Australie"><noRegion><name sortKey="Conus, Philippe" sort="Conus, Philippe" uniqKey="Conus P" first="Philippe" last="Conus">Philippe Conus</name>
</noRegion>
<name sortKey="Cotton, Sue" sort="Cotton, Sue" uniqKey="Cotton S" first="Sue" last="Cotton">Sue Cotton</name>
<name sortKey="Cotton, Sue" sort="Cotton, Sue" uniqKey="Cotton S" first="Sue" last="Cotton">Sue Cotton</name>
<name sortKey="Mcgorry, Patrick D" sort="Mcgorry, Patrick D" uniqKey="Mcgorry P" first="Patrick D" last="Mcgorry">Patrick D. Mcgorry</name>
<name sortKey="Mcgorry, Patrick D" sort="Mcgorry, Patrick D" uniqKey="Mcgorry P" first="Patrick D" last="Mcgorry">Patrick D. Mcgorry</name>
</country>
<country name="Allemagne"><region name="Hambourg"><name sortKey="Schimmelmann, Benno G" sort="Schimmelmann, Benno G" uniqKey="Schimmelmann B" first="Benno G" last="Schimmelmann">Benno G. Schimmelmann</name>
</region>
<name sortKey="Lambert, Martin" sort="Lambert, Martin" uniqKey="Lambert M" first="Martin" last="Lambert">Martin Lambert</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PoplarV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001221 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001221 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Bois
   |area=    PoplarV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:28477070
   |texte=   Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:28477070" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a PoplarV1

This area was generated with Dilib version V0.6.37.
Data generation: Wed Nov 18 12:07:19 2020. Site generation: Wed Nov 18 12:16:31 2020

	Serveur d'exploration sur le peuplier
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le peuplier

Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.

Rates and predictors of 18-months remission in an epidemiological cohort of 661 patients with first-episode psychosis.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki